Archive - Provisional Agenda:

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Presentation slides will be made available to delegates shortly after the conference.

Day 1: October 18th

08:00 Registration

09:00 RNAi in Drug Development Chaired by Dr Dmitry Samarsky

09:05 Understanding basic biology of RNAi through product development -Dr Dmitry Samarsky, Technology and Business Development, Invitrogen

09:40 Recent Advances in siRNA Technology for Application in Drug Discovery Research and Development - Dr William Marshall , Executive Vice President, Dharmacon 

10:15 Keynote Speaker, RNAi and Development in C. elegans – Prof. Craig C. Mello, Blais Chair in Molecular Medicine, Howard Hughes Medical Institute, University of Massachusetts

10:55 Coffee and Networking

11:15 Genome-wide siRNA: Development of an Automated, High Throughput siRNA Design & Synthesis Platform - Dr Bettina Hädrich, Manager siRNA and Genomic Services, QIAGEN

11:50 High Throughput Functional Chemogenomics using RNAi for Drug Discovery -Dr David M. Evans, Head of Drug Discovery, Translational Genomics Research Institute (TGEN) 

12:25  Combining siRNA gene knock-down with genome- wide expression profiling: assessment of specificity and analysis of downstream changes in biological pathways - Dr. Tarif A. Awad, Affymetrix Genomics Collaborations

13:00 Lunch and Exhibition

14:15 Delivery and Transfection Chaired by Dr Helmuth van Es

14:20 Nanoplex-mediated delivery of siRNA to inhibit angiogenesis in vivo Dr Raymond Schiffelers, Assistant Professor of Pharmaceutics, Utrecht University

14:55 Evaluation of RNAi in mammals after delivery of siRNA using Hydrodynamic Intravascular Injection Dr David Lewis, Senior Scientist, Mirus

15:30 Novel siRNA Structures Dr Andre Lochter, Director Business Development, atugen

16:05 Coffee and networking

16:25 Highly parallel transfection of siRNA in cell microarrays Dr. Xavier Gidrol, Director of Functional Genomics Laboratory, CEA

17:00 Discovery and Validation of Targets for the treatment of osteoarthritis and asthma using adenoviral siRNA expression libraries - Dr Helmuth van Es, Director – Cellular & Molecular Biology, Galapagos Genomics

17:35 Drinks Reception

18:35 End of day

Day 2: October 19th

09:00 Target Identification and Validation Chaired by Dr David Dorris

09.05 Target Validation of Kinases using highly effective siRNAs Dr David Dorris, Director - RNAi Technologies, Ambion

09:40 Design and Optimisation of Knockdown Reagents according to defined biological criteria Dr Eleanor Barnard, Operations Director, Expression Biosystems

10:15 Application of High Throughput RNAi and over-expression technology to target validation Dr Angelika Bonin-Debs, Head of Molecular and Cell Biology, Xantos Biomedicine

10:50 Coffee and networking

11:10 RNAi for Target Identification and Validation in Drug Development Dr Oliver Steinbach, Director - Functional Cloning, Altana

11:45 Design and application of siRNAs for Target Validation Dr Jens Kurreck, Team Leader, Berlin Free University

12:20 Many commonly used siRNAs risk off-target activity Dr Torgeir Holen, CMBN, University of Oslo

12:55 Lunch and Exhibition

14.25 Therapeutic & in vivo developments Chaired by Dr Nassim Usman

14:30 Modulation of immune responses with siRNA molecules targeting the Notch signalling pathway - Dr Yvette Stallwood, Researcher, Lorantis

15:05 Real-time Quantitation of MicroRNAs by RT-PCR - Dr Caifu Chen, Group Leader, Advanced Research & Technology, Applied Biosystems 

15:40 New developments in siRNA Therapeutics - Dr Nassim Usman, Chief Operating Officer, Sirna Therapeutics

16:15 Coffee and Close of Conference