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Archive - Dr. Joel Bard

Joel Bard obtained his doctorate from Harvard University and, is currently a senior scientist at Wyeth Research. He undertook post-doctoral research at Boston Biomedical Research Institute with Dr. Andrew Bohn, and graduate research at Harvard University with Dr. Ernest G. Peralta. He then moved to his current position at Wyeth and:

• Crystallized and determined structures of potential drug targets and compound-target complexes
• Led implementation of robotic systems for automated setup and imaging of crystallization experiments
• Designed and co-wrote comprehensive software package for design and management of automated crystallization experiments
• Represented crystallography in a multi-disciplinary effort to express, purify, and crystallize membrane proteins

Publications Joel has been involved in are as followes:

Bard J, Kunkel MT, Peralta EG.Single channel studies of inward rectifier potassium channel regulation by muscarinic acetylcholine receptors. J Gen Physiol. 2000 Nov; 116(5): 645-52.

Bard J, Zhelkovsky AM, Helmling S, Earnest TN, Moore CL, Bohm A. Structure of yeast poly(A) polymerase alone and in complex with 3'-dATP. Science. 2000 Aug 25; 289(5483): 1346-9.

Drum CL, Yan SZ, Bard J, Shen YQ, Lu D, Soelaiman S, Grabarek Z, Bohm A, Tang WJ.Structural basis for the activation of anthrax adenylyl cyclase exotoxin by calmodulin. Nature. 2002 Jan 24; 415(6870): 396-402.

Olland AM, Underwood KW, Czerwinski RM, Lo MC, Aulabaugh A, Bard J, Stahl ML, Somers WS, Sullivan FX, Chopra R. Identification, characterization, and crystal structure of Bacillus subtilis nicotinic acid mononucleotide adenylyltransferase. J Biol Chem. 2002 Feb 1; 277(5): 3698-707.

Toth J, Cutforth T, Gelinas AD, Bethoney KA, Bard J, Harrison CJ. Crystal structure of an ephrin ectodomain. Dev Cell. 2001 Jul; 1(1): 83-92.




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